Current concept of reverse cholesterol transport and novel strategy for atheroprotection

Current concept of reverse cholesterol transport and novel strategy for atheroprotection.

Elevated levels of low-density lipoprotein cholesterol (LDL-C) increase the risk of coronary heart disease (CHD), but pharmacologic therapy to decrease LDL-C significantly reduces the risk of cardiovascular events. Despite the effectiveness of statin therapy, there remains significant residual cardiovascular risk. A low plasma concentration of high-density lipoprotein cholesterol (HDL-C) is ass...

Cholesterol efflux and atheroprotection: advancing the concept of reverse cholesterol transport.

Contemporary Reviews in Cardiovascular Medicine Cholesterol Efflux and Atheroprotection Advancing the Concept of Reverse Cholesterol Transport

H igh-density lipoprotein (HDL) has been proposed to have several antiatherosclerotic properties, including the ability to mediate macrophage cholesterol efflux, antioxidant capacity, antiinflammatory properties, nitric oxide–promot-ing activity, and ability to transport proteins with their own intrinsic biological activities. 1 HDL particles are critical acceptors of cholesterol from lipid-lad...

wuthering heights and the concept of marality/a sociological study of the novel

to discuss my point, i have collected quite a number of articles, anthologies, and books about "wuthering heights" applying various ideas and theories to this fantastic story. hence, i have come to believe that gadamer and jauss are rightful when they claim that "the individaul human mind is the center and origin of all meaning," 3 that reading literature is a reader-oriented activity, that it ...

Tachometer for Reverse Cholesterol Transport?

M any clinical and epidemiological studies, as well as meta-analyses thereof, have shown the inverse relationship of high-density lipoprotein cholesterol (HDL-C) and apoliopoprotein (apo) A-I plasma levels with the risk of coronary artery disease. HDL particles and their protein and lipid components exert diverse antioxidative, antiinflammatory, antithrombotic, and cytoprotective effects in vit...